ENGRI1190_HW#4

Res 1997 36 99 108 1 4 pts 2 pts per sketch 1 drop

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Unformatted text preview: ken from: J. Biomed. Mater. Res., 1997, 36, 99-108. 1) (4 pts: 2 pts per sketch; 1 drop; 1 contact angle) Sketch a water droplet on rough PMMA and on rough PMMA after treatment with proteins. In your sketches, label the contact angles. 2) (3 pts) Rank the four surfaces in increasing order of hydrophobicity. 3) (4 pts) Before exposure to proteins, the rough and smooth PMMA have different surface energies. After incubation with protein solutions, the two surfaces have approximately equivalent surface energies. Why? 4) (5 pts) When cells are cultured on the two surfaces, different amounts of extracellular matrix (ECM) is deposited onto smooth PMMA and rough PMMA. Below are two scanning electron micrographs showing the ECM on these two different materials. Which one is which? Justify your assignments. 5) (4 pts) To which surface will cells adhere better? Why? II – Cell adhesion and Biomaterials (15 pts) A research group has experimented with a tissue-engineering scaffold polymerized from monomers of poly(ethylene glycol)-co-poly(...
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This note was uploaded on 01/30/2014 for the course ENGRI 1190 taught by Professor Grubb during the Fall '07 term at Cornell.

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