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Unformatted text preview: ken from: J. Biomed. Mater. Res., 1997, 36, 99-108. 1) (4 pts: 2 pts per sketch; 1 drop; 1 contact angle) Sketch a water droplet on
rough PMMA and on rough PMMA after treatment with proteins. In
your sketches, label the contact angles.
2) (3 pts) Rank the four surfaces in increasing order of hydrophobicity.
3) (4 pts) Before exposure to proteins, the rough and smooth PMMA have
different surface energies. After incubation with protein solutions, the two
surfaces have approximately equivalent surface energies. Why?
4) (5 pts) When cells are cultured on the two surfaces, different amounts of
extracellular matrix (ECM) is deposited onto smooth PMMA and rough
PMMA. Below are two scanning electron micrographs showing the ECM
on these two different materials. Which one is which? Justify your
assignments. 5) (4 pts) To which surface will cells adhere better? Why? II – Cell adhesion and Biomaterials (15 pts)
A research group has experimented with a tissue-engineering scaffold
polymerized from monomers of poly(ethylene glycol)-co-poly(...
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This note was uploaded on 01/30/2014 for the course ENGRI 1190 taught by Professor Grubb during the Fall '07 term at Cornell.
- Fall '07