A b c d e soluble lysosomal proteins will be secreted

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Unformatted text preview: plama membrane None of the above 2. What would be the consequence of treating a cell with a drug that changes the pH of the cis ­ Golgi so that it is the same as the pH of the ER lumen? A) B) C) D) E) Soluble lysosomal proteins will be secreted instead Soluble resident ER proteins will be secreted instead Proteins that are normally secreted will be diverted to the lysosome Proteins that are normally secreted will be retained in the ER lumen O ­linked glycosylation will not occur 3. What would happen to PDI – a soluble resident ER protein – if the last 10 amino acids at the C ­ terminal end were removed? A) B) C) D) E) Truncated PDI will not be translocated into the ER Truncated PDI will be translocated from the ER back into the cytosol Truncated PDI will accumulate in the ER Truncated PDI will accumulate in the cis ­Golgi Truncated PDI will be secreted 4. Hydrolases that normally reside in the ly...
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This document was uploaded on 01/31/2014.

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