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Functioning as gaps for g functioning as phosphatases

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Unformatted text preview: ors / inside the cell The symptoms of the disease cholera are caused by the cholera toxin, which causes covalently modification of certain Gα and inhibits its GTPase activity. This results in: A) B) C) D) E) dissociation of Gβ from Gγ release of Gα from the plasma membrane association of Gα with Gβ and Gγ increased cAMP level over a prolonged period endocytosis of Gα 16. Phospholipase C (PLC): A) B) C) D) E) 17. Activation of phospholipase C (PLC) leads to the following events EXCEPT: A) B) C) D) E) 18. generates substrate for PLC allows proteins with PH domains to be recruited to membranes is critical for cell survival and growth A and B B and C The recruitment of many signaling proteins to the site of activated receptor tyrosine kinase is made possible by: A) B) C) D) E) 21. functioning as GAPs for Gα functioning as phosphatases for receptor kinases binding to GPCRs hydrolyzing cAMP hydrolyzing cGMP PI 3 ­kinase: A) B) C) D) E) 20. increased calcium concentration in the cytosol activation of protein kinase C activation of CaM ­kinase activation of IP3 ­kinase changes in the conformation of calmodulin RGS proteins help to terminate signaling by: A) B) C) D) E) 19. hydrolyzes PI(3,4,5)P3 to generate DAG and IP3 hydrolyzes PI(3,4,5)P3 to generate DAG and PIP2 hydrolyzes PI(4,5)P2 to generate DAG and IP3 hydrolyzes PI(4,5)P2 to generate PI and IP3 hydrolyzes PI(4,5)P2 to generate PI and IP2 the ubiquitination of receptor the binding of arrestin to receptor the binding of E3 to receptor the binding of PH domain ­c...
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