Substance use Disorders Guest Lecture

1993 28 dead by age 40 half by suicide homicide or

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Unformatted text preview: common – 8.2% •  Drug derived from the hemp plant (Cannibis sa(va) •  Acts on CB1 and CB2 receptors ▫  Two cannabinoid brain receptors ▫  High concentraIon in hippocampus –༉  Contributes to memory deficits •  Increased blood flow to emoIon regions ▫  Amygdala and anterior cingulate gyrus •  Decreased blood flow to temporal lobe ▫  Associated with auditory akenIon –༉  Poor performance on listening tasks •  Habitual use leads to tolerance ▫  Withdrawal symptoms also observed Effects of Marijuana •  Major acIve ingredient ▫  THC (delta- 9- tetrahydrocannabinol) •  Psychological ▫  Feelings of relaxaIon and sociability ▫  Rapid shi`s of emoIon ▫  Interferes with akenIon, memory, and thinking –༉  Decline in IQ over Ime ▫  Heavy doses can induce hallucinaIons and panic ▫  Impairment of skills needed for driving –༉  Impairment present for several hours a`er ‘high’ has worn off •  Physiological Bloodshot & itchy eyes Dry mouth and throat Increased appeIte Reduced pressure within the eye ▫  Increased BP ▫  Abnormal heart rate ▫  ▫  ▫  ▫  –༉  May exacerbate pree...
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