Substance use Disorders Guest Lecture

mackillop j courtney k e moni p m mioko k 2013

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Unformatted text preview: lness, yawning ▫  Become more severe and also include cramps, chills/sweaIng, increase in HR and BP, insomnia, & vomiIng Biobehavioral Effects of Opiates •  29 year study of 500 heroin addicts (Hser, et al., 1993) ▫  28% dead by age 40 –༉  Half by suicide, homicide, or accident –༉  One- third by overdose •  Many users resort to illegal acIviIes to obtain money for drugs ▫  The`, prosItuIon, dealing drugs •  Exposure to infecIous diseases via shared needles ▫  e.g. HIV ▫  Evidence suggests that free needles reduces infecIous diseases associated with IV drug use Emergency Room Visits for PrescripIon Opiates SedaIves •  Barbituates ▫  Induce muscle relaxaIon, reduce anxiety, produce mild euphoria ▫  In 1940s prescribed to aid sleep ▫  Usage declined from 1975 thru 1990s but increased recently •  Other syntheIc sedaIves ▫  Benzodiazepines –༉  E.g. Valium •  SImulate GABA system •  Heavy dosages ▫  Slurred speech ▫  Unsteady gait ▫  Impaired judgment & concentraIon ▫  Irritability & combaIveness ▫  Accidental suffocaIon...
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