SUbstance Use Lecture

Damage to endocrine glands and pancreas heart failure

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Unformatted text preview: use drinking ▫  5 drinks, 5 or more Imes in a 30 day period –༉  17.6% prevalence among college students •  Comorbidity is extremely common - 21.3% with AUD also have at least 1 psychological disorder Overview of Drugs of Abuse Acute (Short- term) Effects of Alcohol •  Enters the bloodstream through small intesIne ▫  metabolized by the liver •  Effects vary by blood alcohol concentraIon (BAC) ▫  ConcentraIon varies by gender, height, weight, liver efficiency •  Affects brain areas associated with error monitoring and decision making. •  Biphasic effect ▫  IniIally sImulates – when BAC is rising ▫  Later sedates – when BAC is falling Acute (Short- term) Effects of Alcohol •  Effect of ingesIng large amounts ▫  ▫  ▫  ▫  ▫  Impaired speech and vision Interference in complex thought processes Poor coordinaIon Loss of balance Depression and withdrawal •  Interacts with several neural systems ▫  ▫  ▫  ▫  SImulates GABAA receptors SImulates endogenous opioids Increases dopamine and serotonin Inhibits glutamate receptors Long Term Physiological Effects •  MalnutriIon ▫  Calories from alcohol lack nutrients ▫  Alcohol interferes with digesIon and absorpIon of vitamins from food •  Deficiency of B- complex vitamins ▫  AmnesIc syndrome •  Cirrhosis of the liver ▫  Liver cells engorged with fat and protein impeding funcIoning ▫  Liver disease and cirrhosis rank 12th in US causes of death. •  Damage to endocrine glands and pancreas •  Heart failure •  ErecIle dysfuncIon •  Hypertension •  Stroke •  Capillary hemorrhages ▫  Facial swelling and redness, especially in nose •  DestrucIon of brain cells ▫  Especially areas important to memory NicoIne and Cigareke Smoking •  NicoIne ▫  AddicIng age...
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