Ohta worked to show that slightly deleterious

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Unformatted text preview: allele’s fate will be governed by natural selection. 9. What is the heterozygosity of a locus in Hardy ­Weinberg equilibrium with seven alleles (p+q+r+s+t+u+v = 1.0) with frequencies of 0.1, 0.3, 0.2, 0.2, 0.1, 0.05, 0.05 (2 points)? Write down the formula you used to make your calculations (1 point). Is this a low or a high heterozygosity and why (1 point)? H = 1  ­ p2  ­ q2  ­ r2 ­ s2  ­ t2  ­ u2  ­ v2 (or H=1 ­frequences of homozygotes); H = 1  ­ 0.01 – 0.09 – 0.04 – 0.04 – 0.01 – 0.0025 – 0.0025 = 0.805 10. What is the main factor that influences the rate of decay of Linkage Disequilibrium (ie, how fast the population reaches linkage equilibrium) (2 points)? The degree of genetic linkage between two loci (how close they are on the chromosome). 11. In a few sentences, describe Tomoko Ohta’s most important contribution to the field of evolutionary biology (2 points). Ohta worked to show that slightly deleterious mutations fix at a faster...
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This note was uploaded on 02/02/2014 for the course ECOL 335 taught by Professor Reinthal during the Spring '10 term at University of Arizona- Tucson.

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