February_6_2013_NKW

0036 human 00011 10 11 do living fossils show

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Unformatted text preview: tion of mutations in a population)? K = µ changes/genome region/unit time (units are same for K and µ) 3. What is the relationship between population size and variation? π = 4Neµ What determines the amount of divergence between two species? t Ne = size of ancestral population D = 2µt + 4Neµ 9 Measuring nucleotide diversity in great apes Estimating mutation rates from evolutionary comparisons D = 2µt + 4Neµ t For human-chimp, D = 1.33% for autosomal pseudogenes t = ~5 MYA 1 generation = 20 years, So t = 250,000 generations Ne = 104 – 105 µ per site per generation is ~2 x 10-8 Bonobo π = 0.001 Chimps π = 0.002 Gorilla π = 0.0015 Ne = size of ancestral population Orangtan π = 0.0036 Human π = 0.0011 10 11 Do “living fossils” show slower molecular evolution? Neutral Theory: no because K = µ Selectionists: Yes, rates of morphological evolution (change in body form/unit time) depend on molecular evolution (substitutions/My) horseshoe crab:...
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This note was uploaded on 02/02/2014 for the course ECOL 335 taught by Professor Reinthal during the Spring '10 term at Arizona.

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