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Unformatted text preview: ucture of DNA suggested a mechanism for its replication, yet this mechanism would present “problem” for replicating linear chromosomes: Following replication the two daughter chromatids would theoretically be shorter at one end, with the opposite ends being shorter for the two chromatids. Over time this problem would lead to the loss of DNA from the ends of chromosomes A. What aspect of the DNA structure suggested a model for DNA replication? B. What aspect of their model led them to consider that DNA would be lost from telomeres at each round of DNA replication. C. State why this turns out not to be a “problem” after all in eukaryotes. You can use a diagram if that helps. D. DNA replication of chromosomal DNA is semidiscontinuous. What is the meaning of this term? E. DNA polδ has a 3' to 5' exonuclease activity. What is the purpose of this function? Q 8. A. List six enzymatic activities acting at or near the replication fork during replication. Q 9 You are investigating DNA synthesis in a mammalian tissu...
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