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Is this finding consistent with the cellular

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Unformatted text preview: e steps you would take to answer this question. B. It turns out that your protein is associated with repeated DNA sequences found at the ends of chromosomes. Where might these sequences be located in an interphase nucleus? C. You are able to purify enough protein to carry out mass spectrometry and determine some of its amino acid sequence. You use this peptide sequence to search a database of protein sequences and find that it is closely related to a family of histone deacetylases. Is this finding consistent with the cellular localization of this protein? D. You are interested to know if your protein can deacetylate histones in vitro. You create a chromatin substrate using a 1:2 molar ratio of DNA to purified histones, including acetylat...
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