MCB121+W14+practice+problem+set+1.2

J mark the region where the origin of replication

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Unformatted text preview: ntibody complex 4) removing crosslinks and analyze DNA products using pyrosequencing or by hybridization to microarrays. B. It turns out that your protein is associated with repeated DNA sequences found at the ends of chromosomes. Where might these sequences be located in an interphase nucleus? These sequences will likely be at the nuclear periphery since that is where telomeres are associated. C. You are able to purify enough protein to carry out mass spectrometry and determine some of its amino acid sequence. You use this peptide sequence to search a database of protein sequences and find that it is closely related to a family of histone deacetylases. Is this finding consistent with the cellular localization of this protein? Yes, heterochromatin is also...
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This note was uploaded on 02/03/2014 for the course MCB MCB 121 taught by Professor Gasser,burgess during the Winter '11 term at UC Davis.

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