Review basal ganglia clinically includes subthalamic

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Unformatted text preview: cortex •  Brainstem motor nuclei (ventromedial pathways) –  CorMcal ­basal ganglia loop •  Frontal, parietal, temporal cortex send axons to caudate/putamen •  Caudate/putamen projects to the globus pallidus •  Globus pallidus projects back to motor cortex via thalamic nuclei Anatomy review: Basal ganglia Clinically includes subthalamic nucleus & substanMa nigra These structures are highly interconnected anatomically. nomenclature@@$@#%$#%$ •  Main components of the basal ganglia are the striatum composed of caudate and putamen •  Globus pallidus or pallidum composed of –  globus pallidus externa (GPe) –  globus pallidus interna (GPi) •  SubstanMa nigra composed of –  substanMa nigra pars compacta (SNc) –  substanMa nigra pars reMculata (SNr), •  The subthalamic nucleus (STN) Anatomy review: Basal ganglia Input: striatum { Output: globus pallidus & substanMa nigra Motor “Homunculus” •  Different regions of cortex appear to be the central player in organizing the muscle group(s) for different tasks Parkinson’s Disease •  Some Videos: •  hcp://www.youtube.com/watch? v=qxDmP8c4QUI •  hcp://www.youtube.com/watch? v=8g9vYBPTCN4&feature=related What did you observe while watching these clips? •  Can we make any generalizaMons about the types of movement we saw? Parkinson’s: trouble iniMaMng...
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This note was uploaded on 02/04/2014 for the course BIOG 1440 taught by Professor Owens during the Fall '10 term at Cornell University (Engineering School).

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