Lecture 11 Membranes - Lecture 11 Membranes Basic functions...

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Lecture 11 Membranes Basic functions Membrane lipids Fluidity Membrane carbohydrates Membrane proteins Different types of association with membranes Methods of study of membrane proteins
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Points of the Day Membrane basic structure and function are dependent on the behavior of lipids in the membrane Lipids in the membrane are fluid, that is mobile in the lateral plane of the membrane Proteins associate with the membrane in several different ways. Different environments require different structure.
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Membranes 0
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Define boundaries of cell; permeability barrier Transport solutes Receive Signals; respond to other cells Scaffold for biochemical activities Compartmentalize cells 0
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“Fluid Mosaic Model” 0
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Most Membrane Phospholipids are Phosphoglycerides Amphipathic Nonpolar Polar head group 0
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Glycolipids Sugar faces outside Sphingolipids 0
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Cholesterol On both faces of bilayer 0
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water water Polar head group Polar head group Nonpolar tails 0
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Liposomes: Drug delivery System? 0
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Membrane Fluidity Above Transition Temperature Below Transition Temperature 0
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Cholesterol in the membrane is a “fluidity buffer”. At low temperatures, it increases fluidity, at high temperatures it decreases it. 0
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Lipids are Asymmetrically Distributed in the Membrane 0
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This note was uploaded on 04/08/2008 for the course BIOL 301 taught by Professor Tepperman during the Winter '08 term at University of Cincinnati.

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Lecture 11 Membranes - Lecture 11 Membranes Basic functions...

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