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Unformatted text preview: cytoplasmic dyneins [a force producing protein: minus end
directed motors; powered by ATP hydrolysis)
-kinesins: large ten family in many or ganisms; most move tow ar ds the plus end of MT,
powered by ATP hydrolysis
Dynein H.C. domain str ucture
to consider : there's a "lever arm" that is intramolecular coiled coil alpha helix;
-pow ers the beating strokes of cilia (cilia moves w / pow er str oke, r ecovery str oke)
Evidence that dyne in ar ms dr ive flagellar /ciliary beat via generation of of a sliding force between
adjacent outer doublet Mts
T ake an a...
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- Fall '13