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grow th/elongation of a new filament br anch. As these branches gr ow , the membrane is pushed
forw ar d
F, G, H: capping protein terminated elongation (prevents either addition or loss)
* G: aging of the filament… ages as it goes dow n, gets more ADP-pi, coifilin comes in and
selectively br eaks it up.. at a cer tain point you're pr etty much all ADP.
* H: cofilin has an active state and an inactive state
J: pr ofilin catalyzes exchange of ADP for ATP For the series of questions:
2. if you can't sever, you r un out of ATP
3. Increased expression until you shut it down
4. overexpr essing a plus end capping protein? forw ard movement w ill either slow significantly or
stop Classes of act in binding prot eins:
1. Proteins that cross link actin into loosely order ed networks
2. Proteins that cross link filaments into unipolar bundles
Bundles can act as a single "architectur al unit' and can be moved, pulled on by myosin's
3. Binding proteins that cross link actin into bundles of mixed polarity: these bundles often contain
myosin II bipolar filaments which can induce bundle contraction - can essentially build muscle n
C: proteins t...
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This note was uploaded on 02/05/2014 for the course BIO 102 taught by Professor Chandhoke during the Fall '13 term at Yale.
- Fall '13