Population Genetics Lab.docx - Population Genetics PRE-LAB...

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P RE -L AB Q UESTIONS Assumptions: There are approximately 3,000,000,000 base pairs in the mammalian genome (genes constitute only a portion of this total). There are approximately 10,000 genes in the mammalian genome. A single gene averages 10,000 base pairs in size. Only 1 out of 3 mutations that occur in a gene result in a change to the protein structure. In the mammalian genome: 1. How many total base-pairs are in all the mammalian genes? Population Genetics
2. What proportion (%) of the total genome does this represent?
3. What is the probability that a random mutation will occur in any given gene?
4. What is the probability that a random mutation will change the structure of a protein?
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E XPERIMENT 1: G ENETIC V ARIATION Post-Lab Questions Part 1 1. What is the initial gene pool of beaker #1? Population Genetics
2. What is the initial gene pool of beaker #2?
3. What is the initial gene frequency of beaker #1? Total: 50 a. Blue: 23 b. Red: 27 4. What is the initial gene frequency of beaker #2? Total: 20 a. Green: 13 © eScience Labs, 2018
b. Yellow: 7 5. What can you say about the genetic variation between these populations? Population Genetics
Part 2 1. What is the new gene pool of beaker #1?
2. What is the new gene pool of beaker #2?
3. What is the new gene frequency of beaker #1? Total: 36
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d. Green: 6 4. What is the new gene frequency of beaker #2? Total: 34 a. Blue: 12 b. Red: 12 c. Yellow: 3 d. Green: 7 5.

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