Blood_2012

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Unformatted text preview: ;&=>&2=(&%.))3&=(&&& 3$,+$6($3 %&<&l$(7&(=>,$&Ad&6,/(&6(&6&Aj-&>$*+)/+6>(9=//$+& ,&<&l$(7&(=>,$&$.$J6/$3&;6+/=6.&;+$((*+$&)M&Ad&=(&3$/$,/$3&%5&;$+=;2$+6.& ,2$9)+$,$;/)+(&=>&,6+)/=3&6>3&6)+/=,&%)3=$( 3&<&j)7&(=>,$&/2$&;6+/=6.&;+$((*+$&)M&d"&=>&2=(&%.))3&=(&>)+96. $&<&j)7&(=>,$&Ad&=(&*>6%.$&/)&3=MM&*($&6,+)((&/2$&%.))3I%+6=>&%6++=$+ G<&#2=,2&)M&/2$&M)..):=>C&=(&NOT 6>&6;;+);+=6/$&,)9;)>$>/&)M&6>& 6CC+$((=J$&/+$6/9$>/&;.6>&M)+&A26+.$(a&3=()+3$+_ 6&<&%+$6/2=>C&6&C6(&9=8/*+$&:=/2&2=C2&;$+,$>/6C$&)M&)85C$> %&<&6.@6.=Z6/=)>&)M&/2$&%.))3&K=>,+$6($&/2$&;?L ,&<&;6+/=6.&%.))3&+$;.6,$9$>/&:=/2&>)+96.7&,)9;6/=%.$&:2).$&%.))3 3&<&%+$6/2=>C&C6(&6&9=8/*+$&:=/2&$.$J6/$3&.$J$.(&)M&,6+%)>&3=)8=3$ fetal Hb has higher affinity D! I5X$>5$;-A0);*>-)*>0$F.558$X9>B$Y%f$ F)0*>B9+E$Y% *>$E)0*>0)$>B*+$*>?5;AB0)9<$A)0;;-)0$ KB1A0)F*)9<$5W1E0+$>B0)*A1M$X9..$9+<)0*;0$Y% 89;;5.:08$ 9+$A.*;?*$*+8$;5$*..5X$Y% >5$<5?A0>0$7Y$544$IF6$ "5>0J$F)0*>B9+E$)55?$Y% K9606e$%O^$Y% *>$OGNGM$IF$ 9;$UQ^$;*>-)*>08$;5$F)0*>B9+E$Y% *>$g$OGNG$X9..$"YN$ 9+<)0*;0$F5-+8$Y% <5+>0+>6$$$ D" c)1>B)5A509;9;$KC#7$45)?*>95+M ;>*E0$54$80:0.5A?0+>$$$ A)9?*)1$;9>0;$54$C#7$45)?*>95+$$$ O;> Q$X00/;$$$ 0?F)15+9<$15./$;*<$$$ %+8 >5$'>B ?5+>B$$$ .9:0)$*+8$;A.00+$$$ *8-.>$$$ )08$F5+0$?*))5X$K?10.598$>9;;-0M H :0)>0F)* H ;>0)+-? H )9F; H ;/-.. H ;<*A-.* H A0.:9; DD c...
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This document was uploaded on 02/03/2014.

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