Rely on model selec on methods robust to irrelevant

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Unformatted text preview: ror metric: Root mean squared devia-on (RMSD) ALS Predic-on Prize: Evalua-on   Oct. 1, 2012: Test set released to contestants   The Final Contest Data •  918 training pa-ents + 279 test pa-ents   12 months of data (demographic, ALSFRS, vital sta-s-cs, lab tests) •  625 valida-on pa-ents determined prize winners   Data never seen by contestants, no prior feedback given   Tests ability to generalize to new pa-ents Our Approach Featuriza;on •  Sta-c Data •  Time Series Data Modeling and Inference •  Bayesian Addi-ve Regression Trees Post ­hoc Evalua;on •  BART Performance •  Feature Selec-on •  Model Comparison Featuriza-on   Goal: Compact numeric representa-on of each pa-ent •  Features will serve as covariates in a regression model •  Most extracted features will be irrelevant •  Rely on model selec-on / methods robust to irrelevant features Issue: Features manually specified by non ­expert (me) Open Ques;on: Automa;c featuriza;on of longitudinal data? Featuriza-on   Goal: Compact numeric representa-on of each pa-ent •  Features will serve as covariates in a regression model •  Most extracted features will be irrelevant •  Rely on model selec-on / methods robust to irrelevant features   Sta;c Data Demographics Age, Race, Sex ALS History Time from onset, Site of onset Family History Mother, Father, Grandmother, Uncle… 49 …………………… …………………… Categorical variables encoded as binary indicators Featuriza-on   Goal: Compact numeric repres...
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