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Unformatted text preview: eak up and the break-up fragments ﬁlled w/ pdt IS the secretion! Produce lipid, lipid coalesces into
lipid droplet and BULGES OUT
of cell membrane and PINCHES
OFF -- remains surrounded by a bit
of the cell's membrane! Apocrine secretion of lipid droplets in epithelial cells of
mammary gland: Fig. 4-23 Holocrine secretion in sebaceous gland of skin
This is what
Inﬂammation -- the duct
gets CLOGGED with oil! Terminally
cells Mitotic cells Fig. 4-22 Exocytosis is the basis for merocrine secretion in which secretory
granules, formed via the RER-Golgi apparatus continuum, fuse
with the cell membrane, releasing their contents externally.
Secretion is usually at the apical end and the cells are “polarized”
from one end to the other.
POLARIZED -- basal end is BASOPHILIC bc of a ton of ROUGH ER down there! pancreas secrete
bc of all the
secreting! referred to
tubules. Fig. 4-24 Two kinds of merocrine secretion can be distinguished by H&E
staining of glands:
1. Serous: well-stained secretory granules containing protein
cells makes this glycoprotein called mucin -- super philic -- binds
lots of water -2. Mucous: granules primarily containing mucin, a hydrophilic
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This document was uploaded on 02/04/2014.
- Spring '14