fig 3 3 this large splotch is actually the nucleolus

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Unformatted text preview: KS LIKE HETEROCHROMATIN BUT IT'S NOT!!!!! Fig. 3-3 THIS LARGE SPLOTCH IS ACTUALLY THE NUCLEOLUS!!! CONTAINS INFO TO MAKE RIBOSOMAL RNA!!!! rRNA IS NEVER TRANSLATED BUT AN IMPORTANT COMPONENT IN RIBOSOME PRODUCTION!!!! ACTIVE CELLS THAT ARE MAKING LOTS OF PROTEIN HAVE VERY ACTIVE NUCLEOLI…!!! Fluorescent in situ Hybridization (FISH) of human chromosomes Chromosomal “spread” (or karyotype) from a mitotic nucleus after spreading, photographing, & arranging the chromosomes (Fig. 3-10) Within nucleus, there's a small region for each chromosome within the chromatin!!!!! Each one has their own "territory." Sequence of DNA is known in each of the 23 human chromosomes. Can make RNA probe against specific region in one of the chromosome that, when hybridized, can fluoresce in diff colors under certain wavelengths. Chromosomal territories in the nonmitotic nucleus of a fibroblast in cell culture (Fig. 3-7b) nuclear envelop continuous with rough ER!!! Other important nuclear components include: (1)  the double-membrane called the nuclear envelop, continuous with RER; (2)  the fibrous meshwork of the nuclear lamina (NL), consisting of NL = "scaffolding" -- comes from word "laminated&qu...
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