This preview shows page 1. Sign up to view the full content.
Unformatted text preview: tions: Functions of SMOOTH ER diff than rough! Bc lack ribosomes. 3 important ones:
LIPID SYNTHESIS, DETOXIFICATION, SEQUESTRATION OF CA IONS -- IMP.
IN MUSCLE!!! 1) Site of enzymes for complex
lipid (e.g., steroids) synthesis
2) Site of enzymes that detoxify
various harmful substances
3) Site of membranous structures
for calcium ion sequestration.
So smooth ER stores enzymes used to build complex lipids, detoxify material,
and also store Calcium ions!!!! Cytoplasm filled with smooth ER
often looks “washed out” or poorly
stained because its lipid-rich structure
is dissolved by the organic solvents
used in tissue processing for paraffin
embedding. That can be seen in the
adrenal cells shown here (at right). highly dynamic structure. constantly moving/changing shape! The SER is also an area of transition to the Golgi apparatus. This is a stack of
flat membranous vesicles and is the site of final protein modification and sorting
into transport vesicles. These vesicles form continuously and move through the
“trans Golgi network.” The structure is highly dynamic, with...
View Full Document
- Spring '14