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Unformatted text preview: gestive enzymes.
ex: osteoclast !! although fairly rare in most cells. Fig. 2-17
When a PHAGOSOME gets fused to a LYSOSOME,
material in phagosome broken down & recycled &
If material in phagosome CAN'T be digested,
there may be an accum. of undigestable material
called RESIDUAL BODY. Autophagy:
excess organelles ingested
into lysosome, then broken
down. autophagy: "self" eating.
If organism being starved,
autophagy kicks in. With the TEM (lower right) primary lysosomes are of uniform density, but after
fusing with vesicles, secondary lysosomes (or phagolysosomes) are more
variable. Fig. 2-16 primary lysosomes are ELECTRON DENSE. as they become secondary
lysosomes by fusing to other stuff, they become more heterogenous
& less dense --------> (TEM) Material that cannot be digested
in lysosomes may persist in
residual bodies. These can
accumulate in cytoplasm and
appear in LM as brownish
deposits also called laka Residual body)
can be seen in UNSTAINED cells!
Common in NERVE CELLS? Such stru...
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This document was uploaded on 02/04/2014.
- Spring '14