Or if the new proteins have specific signal sequences

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Unformatted text preview: us or certain organelles). Or, if the new proteins have specific “signal sequences”, they may bind to proteins on the ER (right) forming the “rough ER”, where most proteins in membranes, in secretory If ribosomes free in cytoplasm, they're making FREE vesicles, and lysosomes are produced. Fig. 2-9 proteins, that work in cytoskeleton, or work inside (in cytoplasm) -- POLYSOME Polysome = 2+ ribosomes on same mRNA nucleus…. Bound ribosomes make proteins that are SECRETED, or become membrane proteins. Bound ribosome pdts become sequestered in CERTERNA and then either go into secretory vesicles or go into lysosomes If protein can't be folded properly, its converted to UBIQUITIN and then transferred to a proteosome where broken down into AAs to be re-used. Misfolded proteins are “ubiquitinated” and directed to proteasomes for break down back to into amino acids. CHAPERONES CONSTANTLY MAKING SURE PROTEINS GET FOLDED PROPERLY!!!! smooth ER is mostly LIPIDS. so they typically stain poorly under a microscope! RER can undergo a transition to “smooth ER” which is the site of 3 other major activities or func...
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