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Exam Review - Chapter 17

Beta oxidation by enzymes in mitochondria a three

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Unformatted text preview: yzed by 3 isozymes of acyl- CoA dehydrogenase o Each for different fatty acid lengthgs o All are flavoproteins with FAD as a prosthetic group Figure 17- 8: Four step process of beta oxidation repeats to yield another acetyl- CoA molecule, 1 FADH, 1 NADH, and one H2O o Each molecules of FADH2 formed during oxidation of fatty acids donates a pair of electrons to the electron- transferring flavoproteins of the respiratory chain and produces 1.5 molecules of ATP o Each molecule of NADH delivers a pair of electrons to mitochondrial NADH dehydrogenase to produce 2.5 molecules of ATP Acetyl CoA can be further oxidized in the Citric Acid Cycle to CO2 and H2O Oxidation of unsaturated fatty acids requires two additional reactions An isomerase and a reductase Oleate is an 18- carbon monounsaturated fatty acid with a cis double bond Converted to oleoyl- CoA and enters mitochondrial matrix via carnitine shuttle Undergoes three passes to yield 3 molecules of acetyl- CoA Enoyl CoA isomerase isomerizes the cis conformation to...
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