Exam Review - Chapter 17

They are reconverted to triglycerides and packaged

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Unformatted text preview: of bile salts and triacylglycerols o Micelle formation increases the fraction of lipid molecules accessible to the action of water- soluble lipases Lipases degrade triglycerides into monoglycerides, diglycerides, free fatty acids, and glycerol Fatty acids and other products diffuse into the epithelial cells lining the intestinal surface, where…. They are reconverted to triglycerides and packaged with cholesterol and specific proteins into aggregates called chylomicrons Chylomicrons move from intestinal mucosa into the lymphatic system, and then enter the blood, which carries them to muscle and adipose tissue Lipoprotein lipase: hydrolyzes triacylglycerols to fatty acids and glycerol o Activated by apoC- II Fatty acids are taken up by the cells in the target tissue In muscle, fatty acids are oxidized for energy; in adipose tissue, fatty acids are reesterified for storage as triglycerides Apolipoproteins: lipid- binding proteins in the blood that are responsible for the transport of triglycerides, phospholipids, cholesterol, and cholesterol esters Lipoprotein: spherical aggregates with hydrophobic lipids at the core and hydrophilic protein side chains and lipid head groups at the surface o Combine to form VLDL’s and VHDL’s Hormones trigger the mobilization of stored triacylglycerols Lipids are stored in adipocytes in the form of lipid droplets o Coated with perilipins, family of proteins that restrict access to lipid drople...
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