Exam Review - Chapter 14

Glucose 6 phosphate is converted to fructose 6

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: required 1. Glucose is phosphorylated at C- 6 by hexokinase to yield glucose 6- phosphate a. Reaction is irreversible b. Requires Mg2+ for its activity to shield the negative charges of the phosphoryl groups in ATP 2. Glucose 6- phosphate is converted to fructose 6- phosphate by phosphohexose isomerase a. Frees hydroxyl group on C- 1 for phosphorylation 3. Fructose 6- phosphate phosphorylates to fructose 1,6- bisphosphate by phosphofructokinase- 1 (PFK- 1) a. Reaction is irreversible b. Activity of PFK- 1 is increased whenever the cell’s ATP supply is low 4. Fructose 1,6- bisphosphate is split into glyceraldehyde 3- phosphate and dihydroxyacetone phosphate by adolase 5. Dihydroxyacetone phosphate is isomerized into glyceraldehyde 3- phosphate by triose phosphate isomerase Payoff Phase- Ne...
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online