Exam Review - Chapter 6

Enzymes in their active sites have functional groups

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Unformatted text preview: tion is determined by the concentration of the reactant and by the rate constant, denoted by k rate equation: V= k[S] depending on the number of reactants will determine the order of the reaction Enzymes are catalysts, but how? Enzymes in their active sites have functional groups (amino acid side chains, metal ions, and coenzymes) that form transient covalent bonds with the substrate Covalent interactions lower the activation energy Noncovalent interactions also help lower activation energy in that it creates a more stable environment for the substrate Formation of each weak interaction (hydrogen bonding, hydrophobic, ionic) is accompanied by a release in energy that stabilizes the interaction Binding energy: the energy derived form enzyme- substrate interaction In order to catalyze reactions, the enzyme must be complementary to the reaction transition state However, the tra...
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