BIOC 431 Exam 3 F12

10 points a what is the effect on aconitase activity

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Unformatted text preview: ivity. Be sure to include in your answer the cofactor requirements for PDH (7 points). 7 point Minimal Answer must show: pyruvate as substrate, acetyl- CoA and CO2 as products and TPP, lipoate, CoA, FAD+, NAD+, as cofactors Best answer will show (1 bonus point) the 3 enzymes, with their cofactors and will demonstrate how each functions in the complex. Page | 4 (b) What is the role of pyruvate dehydrogenase complex in cellular energy metabolism? (3 points) Provides acetyl- CoA to the TCA cycle; regulatory to maximize energy utilization from glucose through glycolysis. Other sources of acetyl- CoA that do not proceed though pyruvate do not require the PDH complex [6] The following questions relate to the flow of intermediates and energy production through the TCA Cycle. (5 points) (a) Which enzyme activities are irreversible? [note: correct answer may be enz name or reaction, 3 pts] citrate synthase : OAA + CoASH Citrate isocitrate dehydrogenase: isocitrate + NAD+ α−ketoglutarate + CO2 + NADH + H+ α−ketoglutarate dehydrogenase: α−KG...
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This note was uploaded on 02/06/2014 for the course BIOC 431 taught by Professor Concettadirusso during the Fall '13 term at UNL.

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