BIOC 431 Exam 3 F12

Be sure to include in your answer the cofactor

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Unformatted text preview: in a non- equilibrium state so that work can be done by the system. When a state of equilibrium is reached no further work can be done and the organism is dead. (b) What is meant by a “dynamic steady state” in metabolic control theory? What does it mean for the actual in vivo enzyme activity of multiple reactions in a pathway? (3 points) A dynamic steady state refers to the maintenance of constant levels of pathway intermediates over time, despite their continued synthesis and degradation by enzymes of a metabolic pathway or changes in flux through the pathway Page | 3 (c) The figure below shows a hypothetical pathway from compound A to compounds D along with the control coefficients for the enzyme at each step for the flux from A to D (JAD). Which step would be an ideal target for increasing flux from A to D? Justify you answer in terms of metabolic control. (4 points) Step C to D as the enzyme at this step has the most control over the flux from A to D. [5] The following questions refer to the pyruvate dehydrogenase complex: (a) Write the reaction for pyruvate dehydrogenase complex act...
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