Nutrition B Slides 02.20

Drugs should be used in combination drugs with diet

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Unformatted text preview: omitant risk factors or diseases (hypertension, dyslipidemia, CHD, type 2 diabetes, sleep apnea) Pharmacotherapy (continued) (continued) Drugs should never be used alone. Drugs should be used in combination Drugs with diet, exercise, and behavior modification. modification. Weight Loss Drugs Weight Drug Action Adverse Effects Sibutramine* Norepinephrine, Norepinephrine, Increase in heart Increase (Meridia) rate and blood pressure. rate dopamine, and serotonin reuptake *NOTE: FDA withdrew from US market Oct. 8, 2010 *NOTE: http://www.businessweek.com/lifestyle/content/healthday/644146.html http://www.businessweek.com/lifestyle/content/healthday/644146.html Orlistat Orlistat (Xenical) (Xenical) Alli Inhibits pancreatic Inhibits lipase, decreases lipase, fat absorption. decreased fat absorption decreased (nonprescription dosage of Orlistat— ~50% strength) Decrease in absorption of fat-soluble vitamins; of soft stools and anal leakage; gas leakage; same as Orlistat Weight Loss (Bariatric)Surgery Weight Option for limited number of patients with Option clinically severe obesity. clinically • BMI >40 or >35 with co-morbid conditions BMI 40...
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