BME+244+Problem+Set+2+solution

7 leakage h 06 05 04 k n 03 02 01 0 20 0 2 4 6 10 35

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Unformatted text preview: direction. These currents are only significant during the action potential. 1 60 0.9 Channel Gating probablities Membrane Potential, mV 40 20 0 −20 −40 Current applied −60 −80 2 4 6 8 10 12 Time, ms 14 16 18 0.7 Leakage, h 0.6 0.5 0.4 K+, n 0.3 0.2 0.1 0 20 0 2 4 6 1.0 35 10 12 Time, ms 14 16 18 20 0.4 Current, mA/cm2 20 15 gK 10 IK 0.6 gNa 25 ILeakage 0.2 0 −0.2 −0.4 5 0 8 0.8 30 Conductances, mS/cm2 Na+, m 0.8 INa −0.6 0 2 4 6 8 10 Time, msec 12 14 16 18 20 −0.8 0 2 4 6 8 10 12 Time, msec 14 16 18 20 c. Threshold current For an applied current of 5 µA/cm2, the gating probabilities are very close to zero and there is little potential change. At 15 µA/cm2, the potential rises slightly...
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