Lecture 7 - Reproductive system

G pneumonia kaposis sarcoma tuberculosis aid syndrome

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Unformatted text preview: th is caused by the action of opportunistic diseases – No immune system protection – Diseases that normally are harmless or can be defended against can kill • E.g., pneumonia, Kaposi’s sarcoma, tuberculosis • AID + Syndrome = a collection of diseases that develops after the immune system is down [occur together] During HIV infection, the virus attacks and destroys the infection-fighting CD4 cells (T-helper cells) of the body’s immune system. – Loss of CD4 cells makes it difficult for the immune system to fight infections. HIV- viral structure Three enzymes carry out later steps in the virus's life cycle: - reverse transcriptase (RT) - integrase - protease -All are drug targets Source: www.niaid.nih.gov HIV life cycle The host cell becomes a factory for the virus Lytic stage = cells lyse and release new virus particles Lysogenic stage = DNA integrated into the host cell nucleus - Virus becomes a part of the cell -Reactivated years later =Full-blown AIDS Source: www.niaid.nih.gov HIV-AIDS progression Source: www.niai...
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