Lecture 7 - Reproductive system

The blood has a high number of hiv copies viral load

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Unformatted text preview: d.nih.gov HIV-AIDS - stages • Stage 1: Primary HIV infection // Acute Primary Infection – HIV enters the body • infects a large number of CD4+ T cells and replicates rapidly. • the blood has a high number of HIV copies (viral load) that spread throughout the body – seeding in various organs, particularly the lymphoid organs (thymus, spleen, and lymph nodes) – the virus may integrate and hide in the cell’s genetic material (DNA) = LYSOGENY – Shielded from the immune system, the virus lies dormant for an extended period of time. – up to 70 percent of HIV-infected people suffer flu-like symptoms. HIV-AIDS - stages – The Immune System Strikes Back – 2- 4 weeks after exposure to the virus, the immune system fights back with killer T cells (CD8+ T cells) and B-cellproduced antibodies. – HIV levels in the blood are dramatically reduced – At the same time, CD4+ T cell counts rebound • for some people the number rises to its original level. HIV-AIDS - stages • Stage 2: Clinical Latency (Dormancy) or...
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