2813228 Medical (2).docx - 1 BIOINFORMATICS BY(Name Course...

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1 BIOINFORMATICS BY (Name) Course Professors Name Institution Location of institution Date
2 Bioinformatics The main aim of molecular biology is to explain the flow of information found in genes in form of DNA, which is transcribed into RNA and then translated into proteins. The expression of this information altered by environmental factors defines the phenotype of a living being. Accordingly, the transcription of genes into RNA molecules identifies the identity of a cell and controls its biological activities. These RNA molecules are important in the interpretation of genome functional structures and knowing its development and diseases as explained in this essay. Identification of RNA in biology is a significant problem particularly in transcriptomes of eukaryotes and coding systems. The analysis of eukaryote transcriptomes is carried out by the use of sequencing experiments that is a deep short-read of complementary DNAs, which are then compared to annotated junctions and a genome to denote biological meaning. Accordingly, long- read complementary datasets of DNA are used to analyze the eukaryotic transcriptome which then produces large datasets in HeLa S3 and human K562 cell lines (Lee et al., 2008, p. 30). Gene expression is the procedure that the nucleotide sequence is utilized to produce cell structures and direct protein syntheses. In this regard structure genes is code for amino acid sequencing. There are two steps in gene expression: transcription and translation. The translation is an expression where information decoded from a gene is utilized to bring about a functional product, for instance, protein. The main aim of this process is to produce a copy of RNA in a gene of a DNA sequence. In the case of a protein-coding gene, it is the RNA copy that transports the information required to construct a polypeptide. The transcription of eukaryotic is meant to pass some processes before it is translated into proteins. Transcription has four stages initiation,
3 elongation, termination, and processing (Lee et al. 2008, p.33). The translation is the second step in gene expression in which the mature mRNA molecule is utilized to act as a template for assembling a series of amino acids to produce a polypeptide that has a specified amino acid sequence. The process occurs in the ribosome, which is a combination of ribosomal RNA and ribosomal proteins RNA (rRNA). The process also has four stages: initiation, elongation, termination, and post-translation processing of the protein (Lee et al., 2008, p.36).

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