Objective 9 objective identify factors which must be

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Unformatted text preview: ole® = sulfisoxazole and erythromycin. • Trimethoprim-sulfamethoxazole (TMP-SMZ) is an especially effective combination with a greatly expanded spectrum. Uses: urinary tract infections, bacterial respiratory infections, gastrointestinal infections. – Septra® , Bactrim ® , and others. Note That We Have Skipped: Note • Antivirals – Amantadine (virus does not enter susceptible cells) – (inhibits DNA polymerase at thymine) • Antifungals (disrupt fungal cell membranes) – amphotericin B – Nystatin • Antiparasitic agents – Metronidazole (Flagyl®) • Bind DNA in anerobes but mechanism in parasites is unknown See articles. Objective 9 Objective • Identify factors which must be considered when selecting an antiinfective agent for topical use. Considerations: Topical Antiinfectives Considerations: Antiinfectives • Effectiveness vs. tissue destruction • Nature and concentration of antiseptic – – – – – some are disinfectants as well germicidal not germistatic broad sp...
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This document was uploaded on 02/07/2014.

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