Photosensitivity use sunscreen superinfection a

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Unformatted text preview: , are carried to site of infection, and inhibit proinflammatory cytokines. Especially useful in respiratory infections including cystic fibrosis. s: minocycline. s minocycline minocycline. • Broad spectrum – Effective against Rickettsiae, Mycoplasma, Chlamydia, Amoebae, and many gram positive and gram negative bacteria. Not fungi, though. • Bacteriostatic (Blocks protein synthesis) • Other Issues – May permanently discolor children's teeth if used from fourth month of fetal life though eighth year of childhood. – Photosensitivity (use sunscreen). – Superinfection a problem with chronic therapy (acne). – Need food in stomach but not milk or antacids. – May decrease effectiveness of oral contraceptives. Lincosamides Lincosamides • Examples: – Lincomycin – Clindamycin (Cleocin T®) • Bacteriostatic – inhibits protein synthesis • Used in penicillin allergic patients after less toxic alternatives have failed. • Broad spectrum – Is drug of choice in some cases:...
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