To stable cancer is in g0 difficult to kill with

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Unformatted text preview: mpairment of normal cellular maturation – Undifferentiated cells (often no useful function) Antineoplastic Agents Antineoplastic Agents Drugs to Treat Cancer • What is cancer? – A disease of cells characterized by: • Impairment of normal cellular control – Invasive and able to metastasize – Does not respond to cell contact • Impairment of normal cellular maturation – Undifferentiated cells (often no useful function) • Impairment of normal cellular division. – Excessive cell growth (due to lack of regulation) Antineoplastic Agents Antineoplastic Agents Drugs to Treat Cancer • Why does this lead to illness or death? – Pressure from tumor growth – Destruction of organ – Systemic Competition for: • Nutrients • Waste disposal G0 Variable Length Why is the Cell Cycle Important Why to Cancer Chemotherapy? to • “Stable" cancer is in G0 – difficult to kill with cycle specific drugs • Cells are in different stages – combinations of drugs are more effective than single agents • More kill = less re...
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This document was uploaded on 02/07/2014.

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