This preview shows page 1. Sign up to view the full content.
Unformatted text preview: take on empty stomach). Antidiarrheics
• Important problem: diarrhea can cause
– Electrolytes and acid-base imbalance • Note: Treatment of chronic diarrhea should be
aimed at the problem
– laxative abuse
– lactose intolerance
– irritable bowel syndrome, Crohn’s disease, etc. Antidiarrheics: Methods of Action
• Demulcents and protectives
– help prevent irritation (limited usefulness) • Absorbents - absorb gas or irritating substance
– bismuth subsalicylate, Kaopectate®, activated charcoal • Astringents - precipitate protein and cover surface of membrane
– prevents further irritation, shrinks tissue • Antiinfectives - if cause is microorganism
– note: do not inhibit peristalsis if microorganism present • Sedatives and antispasmodics - opium preparations and
– Examples: Imodium®, Lomotil®, paregoric are combinations of a narcotic
and an antimuscarinic drug. • Lactobacillus - normalizes intestinal flora.
– Especially good if diarrhea follows antibiotic therapy. Carminatives or antiflatulents
Carminatives or antiflatulents
• Increase motil...
View Full Document
This document was uploaded on 02/07/2014.
- Spring '14