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Unformatted text preview: ace active drugs (Ethanols)
Diluents (water or saline)
Dornase Alfa, a DNAase (Pulmozyme®) specifically for cystic fibrosis.
– Viscosity increases due to DNA which comes
from lysed inflammatory cells. Nasal Decongestants
• Adrenergic agents
– Mechanism of Action - nasal vasoconstriction
– Caution: habituation occurs • Antihistaminics
– OK for allergy, may help relieve cold symptoms • Intranasal Steroids - allergy.
– May increase risk of thrush and prevent healing of
damaged nasal mucosa Objective 4
• Describe the effects of histamine and
identify therapeutic uses, common side
effects, and cautions for the histamine
antagonizing drugs. What Histamine Does
• Contraction of bronchial and intestinal
– H1 receptors • Dilation of arterioles and capillaries and
– H1 receptors • Increases gastric acid secretion
– H2 receptors Histamine Antagonizing Drugs
• Produce opposite effects as histamine
– good for counteracting symptoms of reaction that
has occurred. Only minor effect on histamine
release. • Prevent histamine reaction –”antihistamines”...
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- Spring '14