Use of antitussive is secondary to treatment of

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Unformatted text preview: sis (congenital diseases with dysfunction of exocrine glands. In lung, overproduction of viscid mucus). Use of antitussive is secondary to treatment of source of cough. Example: in some asthmatics, cough is primary symptom - would use a bronchodilator, before an antitussive Narcotic Antitussives Narcotic Antitussives (codeine, etc.) • Mechanism of Action – depresses cough center in medulla of central nervous system • Side Effects and Cautions – Potential for abuse • limits usefulness of narcotic antitussives. – Constipation – depress respiration – cause drug dependency. Nonnarcotic Antitussives Nonnarcotic Usually fewer G.I. symptoms • Mechanism of Action – some are peripherally acting • i.e. benzonatate (Tessalon®) - reduces activity of lung stretch receptors, or benzocaine, a topical anesthetic whose usefulness has not been established – many act centrally as do the narcotics • do not have narcotic side effects • dextromethorphan- half as potent as codeine, no prescription necessary = an isomer of codeine tha...
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