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Unformatted text preview: – Peptic ulcer
– Heartburn (may increase tone of lower esophageal
sphincter) • Kinds
– Systemic antacids
Sedative or Antisecretory Agents
Increase gastric emptying Ulcers: Gaps in Epithelium
Ulcers: Acute Peptic Ulcer
Acute Chronic Peptic Ulcer
Chronic Duodenal Ulcer
X-Rays Ulcer Sliding
Sliding Rolling Systemic Antacids
sodium bicarbonate • Not commonly prescribed by physician
because may cause systemic alkalosis and
• Side effect: kidney must then adjust for
– Note: Found in effervescent products such as
Alka Seltzer® and instant Metamucil®.
– CO2 gas and electrolyte imbalances may
stimulate more acid production. Nonsystemic Antacids
– Form insoluble products so not absorbed
– Neutralize hydrogen ion • Examples:
– Aluminum compounds (Rolaids®) and calcium compounds
• Calcium may actually stimulate more acid production later (i.e. excessive
milk drinking not a good idea). – Magnesium compounds (Milk of Magnesia) •...
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This document was uploaded on 02/07/2014.
- Spring '14