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G androgen insensitivity syndrome ais 5 alpha

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Unformatted text preview: rls to preserve reproductive capacity (surgery) Types of Intersex • Genetic XYs ( e.g. androgen insensitivity syndrome, AIS; 5 alpha reductase deficiency) • Genetic XXs ( e.g. Adrenogenital Syndrome/Congenital Adrenal Hyperplasia,CAH) Androgen Insensitivity Syndrome (Genetic XYs) • Basic Problem = males secrete normal levels of androgens but cells are insensitive • Do not develop internal male structures (e.g. prostate, seminal vesicles etc) • Do not develop Fallopian tubes, uterus, upper vagina etc. • Develop a normal clitoris & short vagina • Have undescended testes • At puberty respond to presence of female hormones & undergo breast development & female pelvic changes Androgen Insensitivity Syndrome- AIS AIS Typically not discovered until puberty Reared as girls Develop gender identity as women Look...
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