smallest score at root is minimum weighted in this

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: with each leaf labeled by elements of a k- leYer alphabet and a k x k scoring matrix (δij) A T G C A 0 3 4 9 T 3 0 2 4 GC 49 24 04 40 Weighted Parsimony Score: 22 Sankoff’s Algorithm •  Check children’s every vertex and determine the minimum between them •  An example •  Output: Labeling of internal verJces of the tree T minimizing the weighted parsimony score 4 9/24/13 Sankoff Algorithm: Dynamic Programming Sankoff Algorithm (cont.) •  Begin at leaves: •  Calculate and keep track of a score for every possible label at each vertex –  If leaf has the character in quesJon, score is 0 –  Else, score is ∞ –  st(v) = minimum parsimony score of the subtree rooted at vertex v if v has character t •  The score at each vertex is based on scores of its children: –  st(parent) = mini {...
View Full Document

This note was uploaded on 02/10/2014 for the course CS 425 taught by Professor Asaben-hur during the Fall '13 term at Colorado State.

Ask a homework question - tutors are online