Next idenfy the gene problems many unrelated common

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Certain diseases (cancers) are marked by an abundance of these events Recombina/on 00000000 11111111 00011111 Not all DNA recombines! Gene Conversion •  Gene conversion versus single crossover; hard to dis/nguish in a popula/on Iden/fying the Gene/c Basis of a Phenotype Abstrac/on of a Causal Muta/on A possible strategy is to collect cases (affected) and control individuals, and look for a muta/on that consistently separates the two classes. Next, iden/fy the gene. Problems •  Many unrelated common muta/ons, around one every 1000bp •  We may not sample the causal muta/on. Case Control How to Hunt for Disease Genes Case...
View Full Document

Ask a homework question - tutors are online