Bio 105 Study Guide

Bio 105 Study Guide - Bio 105 Midterm Study Guide (bold =...

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Unformatted text preview: Bio 105 Midterm Study Guide (bold = important) Terms: gene allele dominant recessive genotype phenotype homozygous heterozygous testcross telomere centromere sister chromatid metaphase plate karyotype homologue haploid diploid aneuploid ploidy nondisjunction linked genes homogametic sex heterogametic sex hemizygous autosome sex chromosome incomplete dominance codominance X inactivation Barr body dosage compensation heterozygote advantage recessive lethality (lethal alleles) multiple alleles coupling conformation repulsion conformation chiasmata recombination frequency map distance interference Concepts: Punnett squares Mendel's 1st Law (segregation) Mendel's 2nd Law (independent assortment) Mendelian ratios for 1 gene, 2 genes mitosis meiosis (OMGknowthis!!!) chromosome theory of inheritance sex determination in fruit flies, humans X inactivation / genetic mosaic pedigrees biochemical basis for dominance recessive lethality Examples to understand: Mendel's pea plants Morgan's fruit flies (red eyes, white eyes) trisomy 21 (Down's syndrome) calico (tortoise shell) cats hemophilia pedigree for Queen Victoria's family 4 o'clock plants linked genes recombination (draw out what happens!) gene mapping parental vs. recombinant progeny calculating RF (map distance) accuracy of map units over long distances double crossovers what they can tell you 3 point crosses 4 possible linkage relationships for 2 given genes different rates of recombination seen in males and females MN blood groups ABO blood groups sickle cell anemia curly wing (Cy) allele in Drosophila handedness situs inversus gene in mouse ...
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This note was uploaded on 04/07/2008 for the course BIO 105 taught by Professor Sullivan during the Spring '08 term at UCSC.

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