Lecture 1-Chp2 - Biochemistry 370/670 Macromolecules and...

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Biochemistry 370/670 Macromolecules and Metabolism Lindsay R. Comstock TR 12:30 – Section B 1
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Course Objectives Understand the basic building blocks of biological macromolecules Compare the organization of macromolecules Learn the catalytic mechanisms of key enzymes Learn how free energy changes dictate which biochemical events will occur Understand metabolic pathways Correlate defects with disease Note landmark discoveries that brought us to biotech/postgenomic age 2
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Success In The Course Class attendance & participation Clickers Reading the text(s) Working assigned problems from the text Completing written assignments Thinking chemically Enzyme mechanisms 3
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Resources Textbook “Lehninger Principles of Biochemistry”- 5 th edition Optional study guide “The Absolute, Ultimate Guide to Lehninger Principles of Biochemistry” Textbook web page Course web page Sakai Professor Comstock! 4
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Semester Overview Building blocks Structure of biomolecules Catalysis Signaling Bioenergetics Metabolism Regulation 5
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Biochemistry is “Young” 1828 Synthesis of urea (Wöhler)
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