06BIS101S2013DomRecLect6

The ia and ib alleles code for different antigens

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Unformatted text preview: ntigens are sugar molecules The (fucose and N-acetylgalactosamine) that are connected to proteins on the surface of the red blood cell. ­ The human immune system will recognize these antigens as The “self” and not develop antibodies to those antigens present. Therefore… Therefore… ­Question; where are the antigens that produced the antibodies on the O Question; type blood? ­Answer; common gut bacteria have surface sugars very similar to the A and Answer; B blood group antigens. The immune system makes antibodies to these Ablood like and B-like bacterial antigens. 02/12/14 BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez ©2013 BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez 31 Codominance of A/B blood group antigens In A/B/O blood groups, both the IA In and IB alleles are observed in the heterozygote. The IA and IB alleles code for different antigens antigens (glycoproteins) displayed on the displayed surface of the red blood cell. The (i) allele expresses no allele glycoproteins and produces the O blood group. As can seen at the...
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