10BIS1012013EuKTranscLect10

Genes eukaryotic promoters are similar to eukaryotic

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Unformatted text preview: yotic Transcription ­Eukaryotes use 3 different RNA Eukaryotes polymerases (RNAPs) to transcribe genes. genes. ­Eukaryotic promoters are similar to Eukaryotic prokaryotic promoters in that they have three conserved regions needed for proper promoter function: q the Cap site, q the TATA Box and q the CAAT Box. the ­Eukaryotic mRNAs are typically Eukaryotic monocistronic, compared to the monocistronic compared polycistronic mRNAs found in polycistronic prokaryotes. prokaryotes. ­Eukaryotic mRNA is extensively Eukaryotic modified before it is used to make protein. Processing includes capping, capping tailing and splicing. tailing splicing BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez ©2013 BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez 4 Eukaryotes Use 3 Different RNAPs* E.coli RNAP, ~480kDal, 4 subunits E.coli plus sigma. plus RNAPI, ~470 kDal, 13 subunits, very RNAPI, insensitive to fungal toxin, α-amanitin, -amanitin, transcribes rRNA genes 17S, 25S and 5.8S (S values for yeast rRNA). Ribosomal RNA is extensively proce...
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This note was uploaded on 02/12/2014 for the course BIS 101 taught by Professor Simonchan during the Spring '08 term at UC Davis.

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