12BIS1012013TranslatLect12

The 3 acc end is common to all trnas and forms a bond

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Unformatted text preview: iguez 18 Peptide Bond Formation BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez ©2013 BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez 19 Requirements for Translation ­ mRNA (codons) ­ Ribosomes ­ Transfer RNA (tRNA) ­ Aminoacyl synthetase ­ Amino acids ­ Initiation, elongation and termination Initiation, factors factors ­ ATP, GTP BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez ©2013 BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez 20 Transfer RNA structure – tRNA ­ Transfer RNAs are 70-90 bases long and provide the first of two links between Transfer mRNA and amino acids. The 3’ ACC end is common to all tRNAs and forms a bond mRNA ACC with the proper (cognate) amino acid and the three bases in the anticodon loop hydrogen bonded with a complementary codon in the mRNA. There must be at least as many different tRNAs as there are amino acids but in reality, there are more. more. BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez ©2013 BIS101­001, Spring 2013—Genes and Gene Expression, R.L. Rodriguez 21 L-Form Structure of tRNA ­ Intramolecular comple...
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This note was uploaded on 02/12/2014 for the course BIS 101 taught by Professor Simonchan during the Spring '08 term at UC Davis.

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