11.18.05 - November 18, 2005 Common to all sensory systems...

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November 18, 2005 Common to all sensory systems Photoreception rhodopsin - G protein that binds to retinal Retinal + Opsin o Cis trans in book, should be H not CH3 Transduction in Visual Systems 1) Light absorption by rhodopsin (retinal + proteins) 2) Transducin (g-protein) binds GTP, releases subunit 3) Photodiesterase is activated and converts cGMP to GMP 4) cGMP is reduces and Na+ channels close 5) . 6) . - hyperpolarized in light. Depolarized in dark (dark current) - ITS OPPOSITE MOSE EXCITATIONS Coding depolarization spikes code for intensity o weak signal = weak depolarization, lower frequency o strong stimulus = stronger depolarization = higher frequency. Code for stimulus quality fr Sensory Intergration integration: neuronal Accessory structures Receptor Cells Neural Networks Filter, amplify transduction coding signal process Weak stimulus strong stimulus Generator potential
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lateral inhibition in retina: o a cell is inhibited by the o retina: each photoreceptor inhibits its lateral neighbors
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11.18.05 - November 18, 2005 Common to all sensory systems...

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